Searchable abstracts of presentations at key conferences in endocrinology

ea0026p172 | Neuroendocrinology | ECE2011

Age related distribution of the endothelial nitric oxide synthase gene G894T polymorphism: relationship with metabolic-endocrine and cognitive features

Ianas O , Manda D , Heltianu C , Vladoiu S , Popa O , Rosca R , Oros S , Covic M , Joja O

Background: Genetic variants of the endothelial nitric oxide synthase (eNOS) gene have been reported to be associated with vascular disease. We hypothesized that G894T polymorphism might trigger many of the endocrine-metabolic cognitive changes related to aging.Study design: One hundred and eighty subjects aged 55–80+ years with moderately cognitive impairment (MCI) (MMSE<28) (lot 1), 140 age-matched subjects without cognitive impairment (MMSE&#...